Dr Lianne Schmaal is a NHMRC CDF Senior Research Fellow at Orygen, The National Centre of Excellence in Youth Mental Health, and Centre for Youth Mental Health, The University of Melbourne, where she leads a research program focused on ‘Profiling and Prediction in Youth Depression and Suicide’. Her research aims to understand the neurobiological mechanisms underlying the development and course of depression and suicidal behaviours. A key focus of this research program is addressing the heterogeneity of youth mental disorders by defining profiles of youth mental illness that are grounded in underlying biological mechanisms, as well as by developing prediction algorithms for disease onset and progression, treatment response and suicide attempts. Her research integrates clinical, psychosocial, neurobiological and genetic data through computational modeling and machine learning methods. She is the leading PI of the ENIGMA Major Depressive Disorder (MDD) consortium. ENIGMA MDD is an international consortium that evaluates neuroimaging data from >10,000 people from 32 research samples from 14 different countries worldwide. Dr. Schmaal also holds an Honorary position at the Department of Psychiatry, The University of Melbourne.