The Melbourne Centre for Behaviour Change research will focus on Australia’s preventable health burden. Interventions will be co-designed with at-risk members of the public, patients and healthcare professionals to prevent illness, promote health, and manage chronic conditions. Research, research-based intervention design and evaluation will be undertaken in collaboration with health care services and industry partners to ensure relevance and adoption. A wide range of health challenges will be investigated including obesity, physical inactivity, high blood pressure, diabetes, arthritis, asthma, chronic pain, alcohol use, tobacco use, and sexual health promotion. MCBC will be based in the Faculty of Medicine, Dentistry and Health Sciences and include staff with affiliations and appointments across Schools. The centre will also create a network to facilitate collaboration between the many world-class researchers across UoM faculties who are interested in behaviour change research. Research outcomes will include implementation and refinement of State and Federal policy relevant to population health, across, individuals, patients, communities and health services.